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Adam and Hirsa Present Research on the Ring-Sheared Drop Abnormal fibrous, extracellular, proteinaceous deposits found in organs and tissues are associated with neurodegenerative diseases such as Alzheimer’s. (“Amyloid fibril formation in microgravity: Distinguishing interfacial and flow effects” NNX13AQ22G). The Ring Sheared Drop investigation studies the biophysics of protein amyloidogenesis in the absence of gravity in order to study fibril formation at fluid interfaces, in the absence of solid walls. NASA

Researchers across Space Biology and Physical Sciences come together for a special presentation at the May PSI Users Group.

The Ring-Sheared Drop (RSD) is a Microgravity Science Glovebox experiment that launched in July 2019 to the ISS to study shearing flow in the absence of solid walls. The major goals of this project were to adapt and use the RSD module to develop and test predictive models of non-Newtonian flow of high-concentration proteins at the interface.

At the May Physical Sciences Informatics (PSI) User Group, Dr. Joe Adam, Research Scientist at Rensselaer Polytechnic Institute and University Payload Director of the RSD module, presented, “Protein Solution Hydrodynamic Studies in the Ring-Sheared Drop” detailing the history of RSD, research campaigns and data to be released in PSI. This investigation was led by Principal Investigator, Prof. Amir Hirsa of Rensselaer Polytechnic Institute.

The ring-sheared drop interfacial bioprocessing of pharmaceuticals-I (RSD-IBP-I) campaign aimed to study non-Newtonian interfacial hydrodynamics of the blood transport proteins bovine serum albumin (BSA) and human serum albumin (HSA) in microgravity. Specifically, scientific aims focus on the effects of protein primary structure (BSA or HSA), protein concentration and interfacial shear rate on microgravity fluid flow, measured using velocimetry of hollow glass microsphere tracer particles within protein samples. This campaign intended to confer improved understanding of interfacial protein flows in relation to physiology, the environment, and industry relevant to both spaceflight and Earth. Results from this line of research could have applications to in situ pharmaceutical production, tissue engineering, and diseases such as Alzheimer’s, Parkinson’s, infectious prions, and type 2 diabetes.

To encourage collaboration across common areas of BPS’s Physical Sciences and Biology research, PSI invited Ryan Scott, ALSDA lead Scientist, and members of the ADBR (Alz Disease & Brain Resilience) and Parkinson’s AWG subgroups to attendee this month’s meeting which fueled discussions and led to several connections. During the discussions the two relevant collaborative publications that were shared are:

• McMackin, P., Adam, J., Griffin, S. et al. Amyloidogenesis via interfacial shear in a containerless biochemical reactor aboard the International Space Station. npj Microgravity 8, 41 (2022). https://doi.org/10.1038/s41526-022-00227-2
• Nilufar Ali paper resulting in part from a collaboration within the Parkison’s AWG subgroup

Ali, N., Beheshti, A. & Hampikian, G. Space exploration and risk of Parkinson’s disease: a perspective review. npj Microgravity 11, 1 (2025). https://doi.org/10.1038/s41526-024-00457-6

Ring-Sheared Drop – Interfacial Bioprocessing of Pharmaceuticals(RSD-IBP-I) is now accessible in PSI. http://doi.org/10.60555/smat-bb74

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Jul 29, 2025

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As the aviation industry works to design air taxis and other new electric aircraft, there’s a growing need to understand how the materials behave. That’s why NASA is investigating potential air taxi materials and designs to best protect passengers in the event of a crash.

On June 26, 2025, at NASA’s Langley Research Center in Hampton, Virginia, researchers dropped a full-scale aircraft body modeled after an air taxi from a tall steel structure, known as a gantry.

The NASA researchers behind this test and a previous one in late 2022 investigated materials that best absorb impact forces, generating data that will enable manufacturers to design safer advanced air mobility aircraft.

Image Credit: NASA/Mark Knopp

An aircraft body modeled after an air taxi with weighted test dummies inside is being prepared for a drop test by researchers at NASA’s Langley Research Center in Hampton, Virginia. The test was completed June 26, 2025, at Langley’s Landing and Impact Research Facility. The aircraft was dropped from a tall steel structure, known as a gantry, after being hoisted about 35 feet in the air by cables. NASA researchers are investigating aircraft materials that best absorb impact forces in a crash.NASA/Mark Knopp

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On June 26, 2025, at NASA’s Langley Research Center in Hampton, Virginia, researchers dropped a full-scale aircraft body modeled after an air taxi from a tall steel structure, known as a gantry.

The NASA researchers behind this test and a previous one in late 2022 investigated materials that best absorb impact forces, generating data that will enable manufacturers to design safer advanced air mobility aircraft.

Image Credit: NASA/Mark Knopp

'You here now. You weave together the future. So go out and seek, explore'

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NASA Astronaut Kate RubinsNASA

NASA astronaut and microbiologist Kate Rubins retired Monday after 16 years with the agency. During her time with NASA, Rubins completed two long-duration missions aboard the International Space Station, logging 300 days in space and conducting four spacewalks.
 
“I want to extend my sincere gratitude to Kate for her dedication to the advancement of human spaceflight,” said Steve Koerner, acting director of NASA’s Johnson Space Center in Houston. “She is leaving behind a legacy of excellence and inspiration, not only to our agency, but to the research and medical communities as well. Congratulations, Kate, on an extraordinary career.”
 
Rubins’ first mission to the orbiting laboratory began in July 2016, aboard the first test flight of the new Soyuz MS spacecraft. As part of Expedition 48/49, she contributed to more than 275 scientific experiments, including molecular and cellular biology research, and she was the first person to sequence DNA in space. Her work enabled significant advances with in-flight molecular diagnostics, long-duration cell culture, and the development of molecular biology tools and processes, such as handling and transferring small amounts of liquids in microgravity. Rubins also led the integration and deployment of biomedical hardware aboard the space station, supporting crew health and scientific research in space and on Earth.
 
She again launched in October 2020, aboard a Soyuz spacecraft from the Baikonur Cosmodrome in Kazakhstan, taking part in Expedition 63/64. Alongside her crewmates, Rubins spent hundreds of hours working on new experiments and furthering research investigations conducted during her mission, including heart research and multiple microbiology studies. She also advanced her work on DNA sequencing in space, which could allow future astronauts to diagnose illness or identify microbes growing aboard the station or during future exploration missions.
 
“From her groundbreaking work in space to her leadership on the ground, Kate has brought passion and excellence to everything she’s done,” said Joe Acaba, chief of the Astronaut Office at NASA Johnson. “She’s been an incredible teammate and role model. We will miss her deeply, but her impact will continue to inspire.”
 
In addition to her flight assignments, Rubins served as acting deputy director of NASA’s Human Health and Performance Directorate, where she helped guide strategy for crew health and biomedical research. More recently, she contributed to developing next-generation lunar spacesuits, helping prepare for future Artemis missions to the Moon.
 
 
Before her selection as an astronaut in 2009, Rubins received a bachelor’s degree in molecular biology from the University of California, San Diego, and a doctorate in cancer biology from Stanford University Medical School’s Biochemistry Department and Microbiology and Immunology Department. After returning from her second space mission, Rubins commissioned as a major in the U.S. Army Reserve, serving as a microbiologist in the Medical Service Corps. She currently holds the role of innovation officer with the 75th U.S. Army Reserve Innovation Command’s MedBio Detachment, headquartered in Boston. 


A frequent keynote speaker at scientific, educational, and industry events on space biology, biomedical engineering, and human exploration, Rubins has advocated for NASA’s scientific and exploration missions. As she transitions from government service, she remains committed to advancing innovation at the intersection of biology, technology, and space.
 
“It has been the honor of a lifetime to live and work in space,” said Rubins. “I am grateful for the extraordinary advances at NASA, and it was a privilege to serve and contribute to something so meaningful. The mission of exploration continues, and I can’t wait to watch this nation do what once seemed impossible.”
 

Learn more about how NASA explores the unknown and innovates for the benefit of humanity at:

https://www.nasa.gov/

-end-

Raegan Scharfetter

Johnson Space Center, Houston

281-910-4989

raegan.r.scharfetter@nasa.gov

NASA Astronaut Kate RubinsNASA

NASA astronaut and microbiologist Kate Rubins retired Monday after 16 years with the agency. During her time with NASA, Rubins completed two long-duration missions aboard the International Space Station, logging 300 days in space and conducting four spacewalks.
 
“I want to extend my sincere gratitude to Kate for her dedication to the advancement of human spaceflight,” said Steve Koerner, acting director of NASA’s Johnson Space Center in Houston. “She is leaving behind a legacy of excellence and inspiration, not only to our agency, but to the research and medical communities as well. Congratulations, Kate, on an extraordinary career.”
 
Rubins’ first mission to the orbiting laboratory began in July 2016, aboard the first test flight of the new Soyuz MS spacecraft. As part of Expedition 48/49, she contributed to more than 275 scientific experiments, including molecular and cellular biology research, and she was the first person to sequence DNA in space. Her work enabled significant advances with in-flight molecular diagnostics, long-duration cell culture, and the development of molecular biology tools and processes, such as handling and transferring small amounts of liquids in microgravity. Rubins also led the integration and deployment of biomedical hardware aboard the space station, supporting crew health and scientific research in space and on Earth.
 
She again launched in October 2020, aboard a Soyuz spacecraft from the Baikonur Cosmodrome in Kazakhstan, taking part in Expedition 63/64. Alongside her crewmates, Rubins spent hundreds of hours working on new experiments and furthering research investigations conducted during her mission, including heart research and multiple microbiology studies. She also advanced her work on DNA sequencing in space, which could allow future astronauts to diagnose illness or identify microbes growing aboard the station or during future exploration missions.
 
“From her groundbreaking work in space to her leadership on the ground, Kate has brought passion and excellence to everything she’s done,” said Joe Acaba, chief of the Astronaut Office at NASA Johnson. “She’s been an incredible teammate and role model. We will miss her deeply, but her impact will continue to inspire.”
 
In addition to her flight assignments, Rubins served as acting deputy director of NASA’s Human Health and Performance Directorate, where she helped guide strategy for crew health and biomedical research. More recently, she contributed to developing next-generation lunar spacesuits, helping prepare for future Artemis missions to the Moon.
 
 
Before her selection as an astronaut in 2009, Rubins received a bachelor’s degree in molecular biology from the University of California, San Diego, and a doctorate in cancer biology from Stanford University Medical School’s Biochemistry Department and Microbiology and Immunology Department. After returning from her second space mission, Rubins commissioned as a major in the U.S. Army Reserve, serving as a microbiologist in the Medical Service Corps. She currently holds the role of innovation officer with the 75th U.S. Army Reserve Innovation Command’s MedBio Detachment, headquartered in Boston. 


A frequent keynote speaker at scientific, educational, and industry events on space biology, biomedical engineering, and human exploration, Rubins has advocated for NASA’s scientific and exploration missions. As she transitions from government service, she remains committed to advancing innovation at the intersection of biology, technology, and space.
 
“It has been the honor of a lifetime to live and work in space,” said Rubins. “I am grateful for the extraordinary advances at NASA, and it was a privilege to serve and contribute to something so meaningful. The mission of exploration continues, and I can’t wait to watch this nation do what once seemed impossible.”
 

Learn more about how NASA explores the unknown and innovates for the benefit of humanity at:

https://www.nasa.gov/

-end-

Raegan Scharfetter

Johnson Space Center, Houston

281-910-4989

raegan.r.scharfetter@nasa.gov

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