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These sickle cell researchers and advocates are driving change from labs to global stages, transforming lives in the process.

The FDA recently approved three sickle cell drugs, and dozens more are in development

Time lags between discoveries and awards show how the Nobel Prizes reward science

Can you find the number that doesn't belong?

In Absolution, Jeff VanderMeer explores the mysteries in his Southern Reach Trilogy

Science in meter and verse

You have around 35 trillion red blood cells moving around your body at all times. Typically they are rounded and flexible. What happens when they aren’t?

A delightful course on keeping (and cracking) secrets

Letters to the editors for the May 2024 issue of Scientific American

Research is revealing the key to motivating empathy—and making it stick

Days spent in a desk chair can lead to heart disease or cancer. Getting up often and exercising more vigorously can stave off the ill effects

Writers, artists, photographers and researchers share the stories behind the stories

This month’s issue covers the reasons it’s so hard to go back to the moon, the science of empathy and new advances in treating sickle cell disease

Illuminating the experience of people living with sickle cell could improve patients’ lives and enhance all of medicine

A biography of the scientist whose work led to fears of a ‘population bomb’

When different chickadee species meet, they sometimes choose each other as mates—with surprising results

Best baseball batting order; mummies demystified

Improving sickle cell care by expanding treatment options, advancing new therapies and amplifying the voices of people with the disease

A new generation of treatments addresses the trauma that often underlies addiction

In Pillars of Creation, Richard Panek gets up close to the JWST