Scientific American.com

A hormone-free pill, called YCT-529, that temporarily stops sperm production by blocking a vitamin A metabolite has just concluded its first safety trial in humans, getting a step closer to increasing male contraceptive options

Optimists have similar patterns of brain activation when they think about the future—but pessimists are all different from one another, a brain scan study suggests

In only its second year, the International Logic Olympiad is already booming as logic becomes more and more crucial in our ever changing world

Humid heat is blanketing the eastern U.S. this week, exacerbated by “corn sweat” in the Midwest

A SkyWest pilot’s last-second decision could have prevented a collision that air-traffic controllers may not have foreseen

Acknowledging the limits of one’s own knowledge could be as important a signal of expertise as credentials and confidence

The Langlands program has inspired and befuddled mathematicians for more than 50 years. A major advance has now opened up new worlds for them to explore

This episode of Science Quickly goes on an archival adventure in Scientific American’s July 1925 issue.

Discover why some puzzles stump supersmart AIs but are easy for humans, what this reveals about the quest for true artificial general intelligence—and why video games are the next frontier

A 72 percent reduction in federal funding is devastating to math research. The American Mathematical Society is offering $1 million in backstop grants—but it’s likely not enough

Why do computers only work with the numbers 0 and 1? There are machines that process three digits with more efficiency than you might expect

It’s certainly possible to consume water sourced from the icy rings of Saturn, but doing so safely may require extra steps

Dropout.tv’s Brennan Lee Mulligan talks about the emotional and cultural importance of Dungeons and Dragons.

After photographs showed President Donald Trump with swollen ankles and bruised hands, the White House revealed he has chronic venous insufficiency—a blood vessel disease that affects circulation in the legs

The park’s newest hydrothermal feature has an otherworldly milky texture from dissolved silica

Long-awaited results of a three-person IVF technique suggest that mitochondrial donation can prevent babies from inheriting diseases caused by mutant mitochondria

Neuroscientists have found that the brain can wake up in different ways, explaining why some mornings feel like a dream and some feel like a disaster

Scientists are racing to learn as much as possible about the interstellar comet 3I/ATLAS before it fades from view forever

Household energy expenses will rise, as will greenhouse gas emissions, as a result of the Trump administration's One Big Beautiful Bill Act

New deep-brain-stimulation implants for Parkinson’s disease can listen in on brain waves and adapt to treat symptoms. Can this approach target other conditions?